2014 - Volume 2 - Issue 1 Articles
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Research Article | ArticleJanuary 15, 2014 | Pages : 205 - 450Abstract Glioblastoma multiforme (GBM) is a very aggressive and locally invasive tumor. The current standard of care is partial brain radiation therapy (60 Gy) concurrently with the alkylating agent temozolomide (TMZ). However, patients’ survival remains po.....
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Research Article | ArticleJanuary 30, 2014 | Pages : 205 - 450Abstract A variant of the breast cancer MCF-7 cells, termed MCF-7/SNR, was established by chronic and step-wise exposure to SN38, an active metabolite of irinotecan. MCF7/SNR cells were >100-fold more resistant to SN38 than parental MCF-7 cells, while resist.....
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Research Article | ArticleJanuary 30, 2014 | Pages : 205 - 450Abstract Background: Fast-track surgery may allow accelerated recovery in rectal surgery; however, postoperative complications are a cause for concern. We aimed to retrospectively analyze the morbidity and mortality associated with a fast-track protocol for.....
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Mini Review | ArticleJanuary 30, 2014 | Pages : 205 - 450Abstract Conventional chemotherapy with small molecule drugs has been used for many types of cancer for decades. However, the therapeutic efficacy remains less successful, mostly because of poor tumor selectivity and severe adverse side effects which hampered.....